C57BL/6JGpt-Tg(APP,hPSEN1)48/Gpt
FAD2T(APP/PS1)|Strain NO.T005625
Transgenic (Tg)
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- Quantity: - +
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BASIC INFORMATION
| Strain Name: | C57BL/6JGpt-Tg(APP,hPSEN1)48/Gpt |
| Strain Number: | T005625 |
| Official Symbol: | App,Psen1 |
| Strain Strategy: | T005625.FAD2T(APP PS1) strain info.pdf |
| Official Full Name: | amyloid beta (A4) precursor protein,presenilin 1 |
| Also Known As: | Ag,Abpp,Adap,Cvap,Abeta,betaApp,E030013M08Rik,PS1,Ad3h,PS-1,S182 |
| NCBI Number: | 1182019164 |
| Research Areas: | Disease Models,Neurodegenerative diseases,Alzheimer's disease |
| Strain Background: | [N000013] C57BL/6JGpt |
| Modification Type: | Transgenic (Tg) |
| Inventory Status: | Live,Cryopreserved |
| Sale Status: | IF (Available for Distribution) |
| Health Status: | Specific pathogen free (SPF) |
| Publications: | 1. Icariin improves learning and memory function by enhancing HRD1-mediated ubiquitination of amyloid precursor protein in APP/PS1 mice. Journal of Alzheimer's disease : JAD (2025)2. Radiofluorination of 2-Arylquinolin-4-yl Oxypropanamide Derivatives for TSPO Imaging in Neuroinflammatory Murine, Nonhuman Primates, and Human Brain Autoradiography with Insensitivity to the rs6971 Polymorphism. Journal of medicinal chemistry (2025)3. Late-Stage Activation of Toll-like receptor 3 Alleviates Cognitive Impairment and Neuropathology in an Alzheimer's Disease Mouse Model. Molecular neurobiology (2025)4. Calycosin improved long-term memory impairment in the very early of APP/PS1 mice. Brain research (2025) |